Buy Metformin Online - Absorption of glucose in the gastrointestinal tract.
Metformin is oral antihyperglycemic agent that is used to control glucose levels. It does not stimulate insulin secretion, so the level of this hormone in the body of a diabetic does not increase.
Regular use of the antihyperglycemic agent Metformin allows to delay and reduce:
- Absorption of glucose in the gastrointestinal tract.
- Production of glucose by the liver.
Other glycemic effects of Metformin are the increase of insulin sensitivity and increase in glucose absorption in skeletal muscles. Weight stabilization or weight loss facilitation are non-glycemic effects of this medication.
Who can take this drug?
Metformin is produced in the form of immediate-release/extended-release (IR/ER) pills that are prescribed:
- to reduce blood glucose concentrations in people with type 2 diabetes mellitus;
- to delay or prevent long-term complications of diabetes.
Metformin tablets should be used in conjunction with exercise program and low-carb diets. This allows you to quickly achieve the optimal antihyperglycemic effect and provides the best results in treatment.
- IR Metformin tablets are indicated for the treatment of diabetes in patients aged 10 and older.
- ER tablets should be prescribed for antihyperglycemic therapy in adult patients only.
Metformin pills are intended for oral use. They should be taken during meals. This minimizes the risk of gastrointestinal side effects (e.g., diarrhea or vomiting).
Different dosage regimen for Metformin are used for the management of diabetes, and they are not fixed. The daily dose should be individualized according to age, the antihyperglycemic response and the effectiveness of the treatment.
At the beginning of therapy, children are advised to use an oral dose of Metformin 500 mg approximately in every 12 hours. Adults should take a dose of:
- 500 mg once a day at dinner time (for ER tablets).
- 850 mg once daily or 500 mg twice a day (For IR tablets).
If the antihyperglycemic response is insufficient, the daily dose of Metformin is gradually increased, but no more than up to 2550 mg (IR tablets) or 2000 mg (ER tablets) within 24 hours.
Contraindications to hypoglycemic therapy
Metformin tablets should not be used in patients under 10 years of age. ER tablets are not suitable for use in children or adolescents. This medicine should not be used as monotherapy for obesity in diabetic patients.
The antihyperglycemic agent Metformin is contraindicated in patients with:
- Any type of chronic or acute acidosis.
- Severe kidney diseases.
- Intolerance to Metformin or to any of the excipients .
- Insulin-dependent (type I) or unstable diabetes.
Metformin should not be used together with alcohol, in acute alcohol intoxication, as well as in patients with alcoholism.
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